|Type of insulin||How soon it starts working?||How long it lasts?|
|Short acting (regular)||30 minutes||6-8 hours|
|Short acting (analogue)||10 to 20 minutes||3 to 5 hours|
|Intermediate acting (NPH)||1 to 2 hours||12 to 18 hours|
|Long acting (analogue)||50 to 120 minutes||Upto 24 hours|
|Premixed insulin (regular)||30 minutes||24 hours|
|Premixed insulin (analogue)||10 to 20 minutes||24 hours|
|Ultra Long Acting (analogue)||0.5 to 1.5 hours||42 hours|
Premixed insulin can be helpful in following cases:
S Joshi et al. A review of insulin and insulin regimens in type 2 diabetes. SA Fam Pract 2009 97 Vol 51 No 2.
DeWitt DE, Hirsch IB. Outpatient insulin therapy in type 1 and type 2 diabetes mellitus: scientific review. JAMA 2003;289:2254–2264
Human Insulatard pack insert.
Heise T, Nosek L, Bøttcher SG, et al. Ultra-long-acting insulin degludec has a flat and stable glucose-lowering effect in type 2 diabetes. Diabetes Obes Metab 2012a;14:944-50.